David E Cummings Selected Research

Ghrelin

11/2019	Effects of multiple cycles of weight loss and regain on the body weight regulatory system in rats.
4/2014	A twin study of differences in the response of plasma ghrelin to a milkshake preload in restrained eaters.
6/2009	Minireview: Hormonal and metabolic mechanisms of diabetes remission after gastrointestinal surgery.
3/2009	Expression of obestatin and ghrelin in papillary thyroid carcinoma.
7/2008	A novel weight-reducing operation: lateral subtotal gastrectomy with silastic ring plus small bowel reduction with omentectomy.
5/2008	Acyl and total ghrelin are suppressed strongly by ingested proteins, weakly by lipids, and biphasically by carbohydrates.
3/2007	Ghrelin: a link between energy homeostasis and drug abuse?
10/2006	Prospects for an anti-ghrelin vaccine to treat obesity.
9/2006	Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatment.
8/2006	Ghrelin and the short- and long-term regulation of appetite and body weight.

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David E Cummings Research Topics

Disease

26	Obesity 01/2022 - 06/2003
26	Body Weight (Weight, Body) 01/2022 - 05/2002
26	Type 2 Diabetes Mellitus (MODY) 01/2022 - 11/2006
26	Weight Loss (Weight Reduction) 01/2021 - 05/2002
10	Insulin Resistance 01/2018 - 05/2002
5	Hyperglycemia 01/2017 - 02/2006
5	Prader-Willi Syndrome (Syndrome, Prader-Willi) 08/2006 - 07/2002
4	Weight Gain 05/2008 - 01/2005
4	Hyperphagia (Overeating) 08/2006 - 06/2003
3	Inflammation (Inflammations) 01/2017 - 10/2006
2	Overweight 01/2022 - 01/2018
2	COVID-19 01/2020 - 01/2020
2	Neoplasms (Cancer) 08/2019 - 01/2018
1	Pathologic Constriction (Stenosis) 01/2021
1	Fatty Liver 01/2021
1	Frailty 01/2021
1	Diabetes Complications 01/2018
1	Infections 01/2017
1	Heart Arrest (Cardiac Arrest) 08/2015
1	Genetic Predisposition to Disease (Genetic Predisposition) 04/2014
1	Papillary Carcinoma 03/2009
1	Papillary Thyroid Cancer 03/2009
1	Hashimoto Disease (Thyroiditis, Hashimoto) 03/2009
1	Thyroiditis 03/2009
1	Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy) 08/2008
1	Substance-Related Disorders (Drug Abuse) 03/2007
1	Necrosis 09/2006
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 02/2006
1	Nesidioblastosis (Nesidioblastosis of Pancreas) 07/2005
1	Body Weight Changes 05/2005
1	Hyperinsulinism (Hyperinsulinemia) 04/2004
1	AIDS-Related Complex (ARC) 11/2003
1	Lung Neoplasms (Lung Cancer) 06/2003

Drug/Important Bio-Agent (IBA)

33	GhrelinIBA 11/2019 - 05/2002
14	Insulin (Novolin)FDA Link 11/2019 - 05/2002
14	LeptinIBA 11/2019 - 05/2002
14	Glucose (Dextrose)FDA LinkGeneric 11/2019 - 02/2005
14	Hormones (Hormone)IBA 08/2015 - 04/2004
4	Peptides (Polypeptides)IBA 03/2009 - 06/2003
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2017
2	AdiponectinIBA 01/2017 - 09/2006
2	Gastrointestinal Hormones (Hormones, Gastrointestinal)IBA 06/2009 - 01/2005
2	Pharmaceutical PreparationsIBA 12/2006 - 02/2005
2	HDL CholesterolIBA 09/2006 - 12/2003
2	Ghrelin ReceptorsIBA 08/2006 - 11/2003
2	Dietary Fats (Dietary Fat)IBA 02/2005 - 04/2003
2	Messenger RNA (mRNA)IBA 12/2004 - 11/2003
2	Leptin ReceptorsIBA 12/2004 - 11/2003
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2021
1	Protons (Proton)IBA 08/2019
1	TetracyclinesIBA 01/2017
1	FluoroquinolonesIBA 01/2017
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2017
1	AminoglycosidesIBA 01/2017
1	Chloramphenicol (Chloromycetin)FDA Link 01/2017
1	SulfonamidesIBA 01/2017
1	LactamsIBA 01/2017
1	C-Reactive ProteinIBA 01/2017
1	Inflammation MediatorsIBA 01/2017
1	Blood Glucose (Blood Sugar)IBA 06/2016
1	Metformin (Glucophage)FDA LinkGeneric 01/2016
1	CholesterolIBA 08/2015
1	SDMIBA 11/2013
1	Hypoglycemic Agents (Hypoglycemics)IBA 06/2009
1	Colloids (Colloid)IBA 03/2009
1	Melanocortin Receptors (Melanocortin Receptor)IBA 12/2006
1	VaccinesIBA 10/2006
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2006
1	GlucocorticoidsIBA 09/2006
1	Dexamethasone (Maxidex)FDA LinkGeneric 09/2006
1	Insulin Lispro (Humalog)FDA Link 02/2006
1	Isophane Insulin (NPH Insulin)FDA Link 02/2006
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 04/2005
1	Amino Acids FDA Link 02/2005
1	LipidsIBA 02/2005
1	Olanzapine (Zyprexa)FDA Link 01/2005
1	Clozapine (Clozaril)FDA LinkGeneric 01/2005
1	Antipsychotic Agents (Antipsychotics)IBA 01/2005
1	Antidepressive Agents (Antidepressants)IBA 01/2005
1	Mirtazapine (Rexer)FDA LinkGeneric 01/2005
1	Trimipramine (Surmontil)FDA LinkGeneric 01/2005
1	Psychotropic Drugs (Psychoactive Drugs)IBA 01/2005
1	Streptozocin (Streptozotocin)FDA Link 10/2004
1	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2003
1	Octreotide (Sandostatin)FDA LinkGeneric 08/2003
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 08/2003

Therapy/Procedure

25	Bariatric Surgery 01/2022 - 05/2005
20	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2021 - 05/2002
11	Therapeutics 01/2022 - 01/2003
3	Glycemic Control 01/2022 - 02/2006
3	Injections 01/2017 - 06/2016
2	Caloric Restriction 11/2019 - 07/2016
2	Biliopancreatic Diversion 07/2016 - 07/2008
1	Stents 01/2021
1	Obesity Management 01/2021
1	Gastrectomy 07/2016
1	Anesthesia 08/2015
1	Operative Surgical Procedures 08/2015
1	High-Protein Low-Carbohydrate Diet (Atkins Diet) 05/2008
1	Jejunoileal Bypass 11/2006